at Isleta Resort & Casino. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. No Smoking Facility. It's a warm, friendly environment with slot machines. Learn More. With three live entertainment venues, you'll find something around every corner. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. #2 Best Value of 24 Mexico. Must be 21+. The Travel center includes a casino area with 45 slot machines. Sky City Casino is open 24 hours daily. A warm and friendly environment with slot machines at the Main Casino. Our New Mexico casino is open 24/7 daily. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Upcoming Events. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Colorful bingo cards and round bingo balls w/numbers. The Pyramid Cancun · 4, reviews. Excite. Win. Saturdays in. 1. Unwind. . Indulge. Seadust Cancun Family Resort · 6, reviews. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Swirls of Cash. #1 Best Value of 24 Mexico Casino Hotels ; 2. These casinos and gaming sites are owned by 14 New Mexico. Open 24 hours, 7 days a week! What's happening.