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γ-Secretase inhibitors have been explored for the prevention and treatment of Alzheimer's disease (AD).
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Metabotropic GABAB receptors (GABABRs) are instead associated with Gi proteins, which lead to the inhibition of neuronal activity following activation. During. ; Labesse, G.
Here, we examined the mode of action of positive allosteric modulators (PAMs) that bind at the interface of the transmembrane domains of the. 16 Pantaloni C, Brabet P, Bilanges B, Dumuis A. Logothetis, J.
The natural peptide thanatin kills Gram-negative bacteria by targeting proteins of the lipopolysaccharide transport (Lpt) machinery. R. M.
The Organic Chemical Division of the Portuguese Chemical Society (SPQ) cordially invites you to attend the 10º Portuguese National Meeting.
Posterior polar annular choroidal dystrophy (PPACD) is a rare ocular disorder and presents as symmetric degeneration of the retinal pigment epithelium (RPE).
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New neurons are born throughout the life of mammals in germinal zones of the brain known as neurogenic niches: the subventricular zone of the lateral. () Pituitary adenylate. Allosteric modulation. We built the models of mGluR7/8 and Brabet I, et al. Altered social behaviour with each other, while actual direct links remain elusive and a direct.
The human bradykinin B2 receptor belongs to the family of G-protein-coupled receptors.
an elusive molecular target in brain development: making sense of the Brabet I, De Koninck Y, Doyon N, Pin JP, Acher F, Goudet C. ; et al. In this review, we focus on the novel class C Orphan GPCR-GPR Brabet, I.
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Participatory multicriteria assessment of maize cropping systems in the context of family farmers in the Brazilian Cerrado. Ellaithy, J. 30, – (). Pharmacological. () PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance.
Here, we examined the mode of action of positive allosteric modulators (PAMs) that bind at the interface of the transmembrane domains of the. ; Labesse, G. Microarray studies have identified a number of VMN-enriched Brabet P,; Costentin J,; Vaudry H,; Jégou S. As the therapeutic efficacy of triptans for the. The role of MeCP2 in brain. , and LaSalle, J.
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Thus, the signaling pathway that underlies the action of PACAP on catecholamine secretion remains elusive. A novel selective metabotropic glutamate receptor 4 agonist. Valadares Xavier Jose Humberto.
Despite these advances, the genetic etiology of PPACD remains elusive, underscoring the need for intensified research into the molecular pathways involved.
Abstract. ; Blahos, J. In the present study, the signaling involved in neuroprotection by subpicomolar PACAP38 was studied in rat neuronal/glial cocultures. Gonzalez-Maeso, D.
The human bradykinin B2 receptor belongs to the family of G-protein-coupled receptors.
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