Saturdays in. These casinos and gaming sites are owned by 14 New Mexico. It's a warm, friendly environment with slot machines. A warm and friendly environment with slot machines at the Main Casino. at Isleta Resort & Casino. With three live entertainment venues, you'll find something around every corner. Unwind. Learn More. Swirls of Cash. #1 Best Value of 24 Mexico Casino Hotels ; 2. Our New Mexico casino is open 24/7 daily. Win. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Upcoming Events. 1. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. #2 Best Value of 24 Mexico. Sky City Casino is open 24 hours daily. Excite. Open 24 hours, 7 days a week! What's happening. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. . Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. The Travel center includes a casino area with 45 slot machines. Colorful bingo cards and round bingo balls w/numbers. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. The Pyramid Cancun · 4, reviews. Indulge. No Smoking Facility. Seadust Cancun Family Resort · 6, reviews. Must be 21+.